Intermittent hypoxia regulates stem-like characteristics and differentiation of neuroblastoma cells.

Neuroblastomas are the most common extracranial solid tumors in children. Neuroblastomas are derived from immature cells of the sympathetic nervous system and are characterized by clinical and biological heterogeneity. Hypoxia has been linked to tumor progression and increased malignancy. Intermitte...

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Bibliographic Details
Main Authors: Vasantha Kumar Bhaskara, Indra Mohanam, Jasti S Rao, Sanjeeva Mohanam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281893?pdf=render