68Ga-Labeled GX1 Dimer: A Novel Probe for PET/Cerenkov Imaging Targeting Gastric Cancer

68Ga-Labeled GX1 Dimer: A Novel Probe for PET/Cerenkov Imaging Targeting Gastric Cancer

PurposeTo synthesize the dimer of GX1 and identify whether its affinity and targeting are better than those of GX1. To prepare 68Ga-DOTA-KEK-(GX1)2 and to apply it to PET and Cerenkov imaging of gastric cancer.Methods68Ga-DOTA-KEK-(GX1)2 was prepared, and the labeling yield and stability were determ...

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Bibliographic Details
Main Authors: Jipeng Yin, Bo Xin, Mingru Zhang, Xiaoli Hui, Na Chai, Hao Hu, Bing Xu, Jing Wang, Yongzhan Nie, Guangqing Zhou, Guanliang Wang, Hongbing Lu, Liping Yao, Liusheng Chen, Kaichun Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
GX1 dimer
PET imaging
Cerenkov imaging
TGM2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.750376/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.750376/full

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