From Neural Plate to Cortical Arousal—A Neuronal Network Theory of Sleep Derived from in Vitro “Model” Systems for Primordial Patterns of Spontaneous Bioelectric Activity in the Vertebrate Central Nervous System

From Neural Plate to Cortical Arousal—A Neuronal Network Theory of Sleep Derived from in Vitro “Model” Systems for Primordial Patterns of Spontaneous Bioelectric Activity in the Vertebrate Central Nervous System

In the early 1960s intrinsically generated widespread neuronal discharges were discovered to be the basis for the earliest motor behavior throughout the animal kingdom. The pattern generating system is in fact programmed into the developing nervous system, in a regionally specific manner, already at...

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Bibliographic Details
Main Author: Michael A. Corner
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Brain Sciences
Subjects:
sleep ontogeny
tissue culture
multi-electrode recording
spontaneous neuronal activity
cholinergic activation
synchronized bursting
“REM-sleep” hypothesis
forebrain
hindbrain
Online Access:http://www.mdpi.com/2076-3425/3/2/800

Internet

http://www.mdpi.com/2076-3425/3/2/800

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