Subtyping of microsatellite instability-high colorectal cancer

Subtyping of microsatellite instability-high colorectal cancer

Abstract Background Patients with microsatellite instability-high (MSI-H) colorectal cancer (CRC) generally have a better prognosis than patients with microsatellite stable (MSS) CRC. However, some MSI-H CRC patients do not gain overall survival benefits from immune checkpoint-blockade treatment. In...

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Bibliographic Details
Main Authors: Wangxiong Hu, Yanmei Yang, Lina Qi, Jiani Chen, Weiting Ge, Shu Zheng
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Cell Communication and Signaling
Subjects:
Colorectal cancer
Microsatellite instability-high
Subtyping
Tumor-associated macrophages
Tumor-infiltrating lymphocytes
Online Access:http://link.springer.com/article/10.1186/s12964-019-0397-4

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http://link.springer.com/article/10.1186/s12964-019-0397-4

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