Effects of Central Loop Length and Metal Ions on the Thermal Stability of G-Quadruplexes

The central loop of G-quadruplex molecular beacons is a key element to sense target DNA or RNA sequences. In this study, circular dichroism spectroscopy (CD), thermal difference spectrum (TDS), non-denatured non-denaturing gel electrophoresis, and thermal stability analysis were used to investigate...

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Bibliographic Details
Main Authors: Fengjin Hao, Yushu Ma, Yifu Guan
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/10/1863