Towards a molecular basis of ubiquitin signaling: A dual-scale simulation study of ubiquitin dimers.

Covalent modification of proteins by ubiquitin or ubiquitin chains is one of the most prevalent post-translational modifications in eukaryotes. Different types of ubiquitin chains are assumed to selectively signal respectively modified proteins for different fates. In support of this hypothesis, str...

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Bibliographic Details
Main Authors: Andrej Berg, Oleksandra Kukharenko, Martin Scheffner, Christine Peter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-11-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006589