PAR-3 knockdown enhances adhesion rate of PANC-1 cells via increased expression of integrinαv and E-cadherin.

The balance between the adhesion of cancer cells to extracellular matrix and their migratory potential, as well as their proteolytic activity, are important parameters that determine cancer cells invasiveness and metastasis. Since thrombin has been implicated in cancer progression, we studied the ro...

Full description

Bibliographic Details
Main Authors: Liora Segal, Liora S Katz, Hagit Shapira, Judith Sandbank, Elizabeth Geras-Raaka, Marvin C Gershengorn, Yoram Oron
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3974847?pdf=render