Emerging heterogeneous compartments by viruses in single bacterial cells

Here, the authors apply live-cell and in situ fluorescence imaging at the single-molecule level to examine lambda DNA replication in single cells, finding that individual phage DNAs sequester host factors to their own vicinity and confine their replicated DNAs into separate compartments, suggesting...

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Bibliographic Details
Main Authors: Jimmy T. Trinh, Qiuyan Shao, Jingwen Guan, Lanying Zeng
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17515-8