A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia [version 2; referees: 2 approved, 1 approved with reservations]

Background: Paclitaxel-induced peripheral neuropathy is a common and limiting side effect of an approved and effective chemotherapeutic agent. The cause of this nociception is still unknown. Methods: To uncover the mechanism involved in paclitaxel-induced pain, we developed a Drosophila thermal noci...

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Bibliographic Details
Main Authors: Zina Hamoudi, Thang Manh Khuong, Tiffany Cole, G. Gregory Neely
Format: Article
Language:English
Published: F1000 Research Ltd 2018-10-01
Series:F1000Research
Online Access:https://f1000research.com/articles/7-99/v2