UVB irradiation regulates ERK1/2- and p53-dependent thrombomodulin expression in human keratinocytes.

Thrombomodulin (TM) is highly expressed in endothelial cells and acts as a natural anticoagulation factor to maintain circulation homeostasis. TM is an interesting molecule with many physiological functions, including anti-inflammation, anti-thrombosis, and carcinogenesis inhibition. TM can also be...

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Bibliographic Details
Main Authors: Huey-Chun Huang, Tsong-Min Chang, Yu-Jia Chang, Hsin-Yun Wen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3699658?pdf=render