An attenuated replication-competent chikungunya virus with a fluorescently tagged envelope.

BACKGROUND:Chikungunya virus (CHIKV) is the most common alphavirus infecting humans worldwide, causing acute and chronically debilitating arthralgia at a great economic expense. METHODOLOGY/PRINCIPAL FINDINGS:To facilitate our study of CHIKV, we generated a mCherry tagged replication-competent chime...

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Bibliographic Details
Main Authors: Jing Jin, Michael B Sherman, Daniel Chafets, Nuntana Dinglasan, Kai Lu, Tzong-Hae Lee, Lars-Anders Carlson, Marcus O Muench, Graham Simmons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6086482?pdf=render