Validation of Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Derived Vascular Permeability Measurements Using Quantitative Autoradiography in the RG2 Rat Brain Tumor Model

Validation of Dynamic Contrast-Enhanced Magnetic Resonance Imaging-Derived Vascular Permeability Measurements Using Quantitative Autoradiography in the RG2 Rat Brain Tumor Model

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is widely used to evaluate tumor permeability, yet measurements have not been directly validated in brain tumors. Our purpose was to compare estimates of forward leakage Ktrans derived from DCE-MRI to the estimates K obtained using [14C...

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Bibliographic Details
Main Authors: Moira C. Ferrier, Hemant Sarin, Steve H. Fung, Bawarjan Schatlo, Ryszard M. Pluta, Sandeep N. Gupta, Peter L. Choyke, Edward H. Oldfield, David Thomasson, John A. Butman
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Blood brain barrier
tumor permeability
anti-angiogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558607800790

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http://www.sciencedirect.com/science/article/pii/S1476558607800790

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