The neurobiological mechanism underlying hypothalamic GnRH pulse generation: the role of kisspeptin neurons in the arcuate nucleus [version 2; peer review: 4 approved]

This review recounts the origins and development of the concept of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when striking rhythmic episodes of luteinizing hormone secretion, as reflected by circulating concentrations of this gonadotropin, we...

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Bibliographic Details
Main Author: Tony M. Plant
Format: Article
Language:English
Published: F1000 Research Ltd 2020-02-01
Series:F1000Research
Online Access:https://f1000research.com/articles/8-982/v2