HLA Class II Genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 Are Associated With the Antibody Response to Inactivated Japanese Encephalitis Vaccine

HLA Class II Genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 Are Associated With the Antibody Response to Inactivated Japanese Encephalitis Vaccine

Aim: The objective of this study was to evaluate the association of the human leukocyte antigen (HLA) class II genes HLA-DRB1, HLA-DPB1, and HLA-DQB1 with the humoral immune response elicited by inactivated Japanese encephalitis (JE) vaccine (IJEV).Methods: A total of 373 individuals aged 3–12 years...

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Bibliographic Details
Main Authors: Yufeng Yao, Huijuan Yang, Lei Shi, Shuyuan Liu, Chuanying Li, Jun Chen, Ziyun Zhou, Mingbo Sun, Li Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
human leukocyte antigen class II genes
HLA haplotype
inactivated Japanese encephalitis virus vaccine
antibody immune response
association
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00428/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00428/full

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