Lens status influences the association between CFH polymorphisms and age-related macular degeneration: findings from two population-based studies in Singapore.

To determine the differential effects of genetic polymorphism in CFH and ARMS2 on risk of age-related macular degeneration (AMD) between phakic vs. pseudophakic/aphakic eyes.9,529 eyes of 4,918 participants from the Singapore Malay Eye Study and Singapore Indian Eye Study were analyzed. Participants...

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Bibliographic Details
Main Authors: Chee Wai Wong, Jiemin Liao, Gemmy C Cheung, Chiea Chuen Khor, Eranga N Vithana, Jie Jin Wang, Paul Mitchell, Tin Aung, Tien Y Wong, Ching-Yu Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4364964?pdf=render