Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention

During the current COVID-19 pandemic, a need for evaluation of already available drugs for treatment of the disease is crucial. Hereby, based on literature review from the current pandemic and previous outbreaks with corona viruses we analyze the impact of the virus infection on cell stress response...

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Bibliographic Details
Main Authors: Aikaterini Nasi, Stephanie McArdle, Gustav Gaudernack, Gabriel Westman, Cornelis Melief, Johan Rockberg, Ramon Arens, Demetrios Kouretas, Jan Sjölin, Sara Mangsbo
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221475002030336X