Expression of the Major and Pro-Oncogenic H3K9 Lysine Methyltransferase SETDB1 in Non-Small Cell Lung Cancer
SETDB1 is a key histone lysine methyltransferase involved in gene silencing. The <i>SETDB1</i> gene is amplified in human lung cancer, where the protein plays a driver role. Here, we investigated the clinical significance of <i>SETDB1</i> expression in the two major forms of...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-08-01
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Series: | Cancers |
Subjects: | |
Online Access: | https://www.mdpi.com/2072-6694/11/8/1134 |