Expression of the Major and Pro-Oncogenic H3K9 Lysine Methyltransferase SETDB1 in Non-Small Cell Lung Cancer

SETDB1 is a key histone lysine methyltransferase involved in gene silencing. The <i>SETDB1</i> gene is amplified in human lung cancer, where the protein plays a driver role. Here, we investigated the clinical significance of <i>SETDB1</i> expression in the two major forms of...

Full description

Bibliographic Details
Main Authors: Paola Cruz-Tapias, Vlada Zakharova, Oscar M. Perez-Fernandez, William Mantilla, Sandra Ramírez-Clavijo, Slimane Ait-Si-Ali
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/8/1134