Exome Sequencing of an Adult Pituitary Atypical Teratoid Rhabdoid Tumor (AT / RT)

Exome Sequencing of an Adult Pituitary Atypical Teratoid Rhabdoid Tumor (AT / RT)

Atypical teratoid rhabdoid tumours (AT / RT) are rare pediatric brain tumours characterised by bialleic loss of the SMARCB1 tumor suppressor gene. In contrast to pediatric AT / RT which has a simple genome, very little is known about the adult AT / RT genomic landscape. Using a combination of whole-...

Full description

Bibliographic Details
Main Authors: SWETHAJIT eBISWAS, MADELEINE eWOOD, ABHIJIT eJOSHI, NICK eBOWN, LISA eSTRAIN, TOMMY eMARTINSSON, JAMES eCAMPBELL, ALAN eASHWORTH, AMANDA eSWAIN
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Oncology
Subjects:
Adult
exome sequencing
copy number variation
trisomy 8
SMARCB1
Atypical teratoid rhabdoid tumour
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00236/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00236/full

Similar Items