Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease

Molecular mechanisms of neurodegeneration in the entorhinal cortex that underlie its selective vulnerability during the pathogenesis of Alzheimer's disease

The entorhinal cortex (EC) is a vital component of the medial temporal lobe, and its contributions to cognitive processes and memory formation are supported through its extensive interconnections with the hippocampal formation. During the pathogenesis of Alzheimer's disease (AD), many of the ea...

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Bibliographic Details
Main Authors: Olayemi Joseph Olajide, Marcus E. Suvanto, Clifton Andrew Chapman
Format: Article
Language:English
Published: The Company of Biologists 2021-01-01
Series:Biology Open
Subjects:
alzheimer's disease
amyloid beta protein
apoptosis
entorhinal cortex
excitotoxicity
glia activation
inflammation
oxidative stress
tau
Online Access:http://bio.biologists.org/content/10/1/bio056796

Internet

http://bio.biologists.org/content/10/1/bio056796

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