Pressurized intra-peritoneal aerosol chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model

Pressurized intra-peritoneal aerosol chemotherapy (PIPAC): increased intraperitoneal pressure does not affect distribution patterns but leads to deeper penetration depth of doxorubicin in a sheep model

Abstract Background Pressurized Intra-Peritoneal Aerosol Chemotherapy (PIPAC) is an innovative treatment against peritoneal carcinomatosis. Doxorubicin is a common intra-venous chemotherapy used for peritoneal carcinomatosis and for PIPAC. This study evaluated the impact of increased PIPAC intraperi...

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Bibliographic Details
Main Authors: Myriam Mimouni, Christophe Richard, Pierre Adenot, Martine Letheule, Anne Tarrade, Olivier Sandra, Michèle Dahirel, Thomas Lilin, Benoit Lecuelle, Valérie Gélin, Julien Cohen, Arnaud Fauconnier, François Vialard, Cyrille Huchon, Pascale Chavatte-Palmer
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
Sheep
Doxorubicin
PIPAC
Intraperitoneum pressure
Peritoneal carcinomatosis
Online Access:https://doi.org/10.1186/s12885-021-07955-w

Internet

https://doi.org/10.1186/s12885-021-07955-w

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