Effect of Acid‐Suppressive Strategies on Pazopanib Efficacy in Patients With Soft‐Tissue Sarcoma
Pazopanib (PAZ), a tyrosine kinase inhibitor used in the treatment of soft tissue sarcoma (STS), should not be administered with acid‐suppressive medications (ASMs) due to decreased drug solubility. Common practice for patients requiring ASM with PAZ is to separate administration by 12 hours; howeve...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-09-01
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Series: | Clinical and Translational Science |
Online Access: | https://doi.org/10.1111/cts.12648 |