Epitope-associated and specificity-focused features of EV71-neutralizing antibody repertoires from plasmablasts of infected children

Enterovirus 71 is a leading cause of hand-foot-and-mouth disease and herpangina. Here, the authors characterize a large panel of plasmablast-derived IgG mAbs that target the capsid of EV71 to identify neutralizing antibodies induced by natural infection.

Bibliographic Details
Main Authors: Kuan-Ying Arthur Huang, Mei-Feng Chen, Yhu-Chering Huang, Shin-Ru Shih, Cheng-Hsun Chiu, Jainn-Jim Lin, Jen-Ren Wang, Kuo-Chien Tsao, Tzou-Yien Lin
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00736-9