Motor alterations induced by chronic 4-aminopyridine infusion in the spinal cord in vivo: role of glutamate and GABA receptors
Motor neuron degeneration is the pathological hallmark of motor neuron diseases, a group of neurodegenerative disorders clinically manifested as muscle fasciculations and hyperreflexia, followed by paralysis, respiratory failure and death. Ample evidence supports a role of glutamate-mediated excitot...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-05-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00200/full |