Contribution of Mitochondrial Ion Channels to Chemo-Resistance in Cancer Cells

Mitochondrial ion channels are emerging oncological targets, as modulation of these ion-transporting proteins may impact on mitochondrial membrane potential, efficiency of oxidative phosphorylation and reactive oxygen production. In turn, these factors affect the release of cytochrome c, which is th...

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Bibliographic Details
Main Authors: Roberta Peruzzo, Ildiko Szabo
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/11/6/761