A role for Nrf2 in redox signalling of the invasive extravillous trophoblast in severe early onset IUGR associated with preeclampsia.

A role for Nrf2 in redox signalling of the invasive extravillous trophoblast in severe early onset IUGR associated with preeclampsia.

BACKGROUND: Preeclampsia (PE) is characterized by increased lipid oxidation and diminished antioxidant capacity, while intrauterine growth restriction (IUGR) is characterized by impaired invasion of the extravillous trophoblast. Vascular endothelial growth factor (VEGF) has been reported to be alter...

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Bibliographic Details
Main Authors: Nisreen Kweider, Berthold Huppertz, Christoph Jan Wruck, Rainer Beckmann, Werner Rath, Thomas Pufe, Mamed Kadyrov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3467234?pdf=render

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http://europepmc.org/articles/PMC3467234?pdf=render

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