Computational Investigation of Bisphosphate Inhibitors of 3-Deoxy-<span style="font-variant: small-caps">d</span>-<i>manno</i>-octulosonate 8-phosphate Synthase

Computational Investigation of Bisphosphate Inhibitors of 3-Deoxy-<span style="font-variant: small-caps">d</span>-<i>manno</i>-octulosonate 8-phosphate Synthase

The synthase, 3-deoxy-<span style="font-variant: small-caps;">d</span>-<i>manno</i>-octulosonate 8-phosphate (KDO8P), is a key enzyme for the lipopolysaccharide (LPS) biosynthesis of gram-negative bacteria and a potential target for developing new antimicrobial agen...

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Bibliographic Details
Main Authors: Jéssica de Oliveira Araújo, Alberto Monteiro dos Santos, Jerônimo Lameira, Cláudio Nahum Alves, Anderson Henrique Lima
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
KDO8P synthase
<i>Neisseria meningitidis</i>
bisphosphate inhibitors
molecular dynamics
Online Access:https://www.mdpi.com/1420-3049/24/13/2370

Internet

https://www.mdpi.com/1420-3049/24/13/2370

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