Inflammation Induced Sensory Nerve Growth and Pain Hypersensitivity Requires the N-Type Calcium Channel Cav2.2

Inflammation Induced Sensory Nerve Growth and Pain Hypersensitivity Requires the N-Type Calcium Channel Cav2.2

Voltage-gated calcium channels (VGCCs) are important mediators of pain hypersensitivity during inflammatory states, but their role in sensory nerve growth remains underexplored. Here, we assess the role of the N-type calcium channel Cav2.2 in the complete Freund’s adjuvant (CFA) model of inflammator...

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Bibliographic Details
Main Authors: Saumitra Pitake, Leah J. Middleton, Ishmail Abdus-Saboor, Santosh K. Mishra
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Neuroscience
Subjects:
Cav2.2
inflammation
pain
nerve growth
hyperalgesia
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.01009/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.01009/full

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