Pharmacology and clinical potential of oblimersen sodium in the treatment of chronic lymphocytic leukemia

Gautam Borthakur, Susan O'BrienDepartment of Leukemia, MD Anderson Cancer Center, Houston, TX, USAAbstract: Targeted inhibition of the Bcl-2 family of antiapoptotic proteins is expected to improve outcomes in chronic lymphocytic leukemia. Antisense oligonucleotides and small molecule inh...

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Bibliographic Details
Main Authors: O'Brien S, Borthakur G
Format: Article
Language:English
Published: Dove Medical Press 2012-08-01
Series:Blood and Lymphatic Cancer : Targets and Therapy
Online Access:http://www.dovepress.com/pharmacology-and-clinical-potential-of-oblimersen-sodium-in-the-treatm-a10754