The Distribution of Prion Protein Allotypes Differs Between Sporadic and Iatrogenic Creutzfeldt-Jakob Disease Patients.

Sporadic Creutzfeldt-Jakob disease (sCJD) is the most prevalent of the human prion diseases, which are fatal and transmissible neurodegenerative diseases caused by the infectious prion protein (PrP(Sc)). The origin of sCJD is unknown, although the initiating event is thought to be the stochastic mis...

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Bibliographic Details
Main Authors: Roger A Moore, Mark W Head, James W Ironside, Diane L Ritchie, Gianluigi Zanusso, Young Pyo Choi, Suzette A Priola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4740439?pdf=render