Levetiracetam-associated irritability and potential role of vitamin B6 use in veterans with epilepsy

Objectives: Levetiracetam, a commonly prescribed antiseizure medication (ASM), may cause irritability, depression, and anger. The mechanisms underlying these behavioral effects and individual risk factors remain unknown. Mitigation strategies are limited, including discontinuation, supplementation w...

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Bibliographic Details
Main Authors: Emma Dreischmeier, Andrea Zuloaga, Robert J. Kotloski, Ariela O. Karasov, Barry E. Gidal
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Epilepsy & Behavior Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589986421000265