Stationary phase-specific virulence factor overproduction by a lasR mutant of Pseudomonas aeruginosa.

Secreted virulence factors of the human pathogen Pseudomonas aeruginosa are often under quorum sensing control. Cells lacking the quorum-sensing regulator LasR show reduced virulence factor production under typical laboratory conditions and are hypo-virulent in short-term animal infection models, ye...

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Bibliographic Details
Main Author: Matthew T Cabeen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3923063?pdf=render