Nrf2 epigenetic derepression induced by running exercise protects against osteoporosis
Abstract Osteoporosis (OP) is a common skeletal disease involving low bone mineral density (BMD) that often leads to fragility fracture, and its development is affected by multiple cellular pathologies and associated with marked epigenetic alterations of osteogenic genes. Proper physical exercise is...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | Bone Research |
Online Access: | https://doi.org/10.1038/s41413-020-00128-8 |