Physiological and Pathological Function of Serine/Arginine-Rich Splicing Factor 4 and Related Diseases

Serine/arginine-rich splicing factors (SRSFs) have one or two RNA recognition motifs in the N terminal and a serine/arginine-enriched domain in the C terminal. SRSFs are essential components of spliceosomes and are involved in alternative splicing, spliceosome assembly, mRNA export, and nonsense-med...

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Bibliographic Details
Main Authors: Wanyan Tan, Wei Wang, Qingfeng Ma
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/3819719