Combinations of immunotherapy and radiation in cancer therapy

The immune system has the ability to recognize and specifically reject tumors, and tumors only become clinically apparent once they have evaded immune destruction by creating an immunosuppressive tumor microenvironment. Radiotherapy can cause immunogenic tumor cell death resulting in cross-priming o...

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Bibliographic Details
Main Authors: Ralph Eric Vatner, Benjamin Thomas Cooper, Claire eVanpouille-Box, Sandra eDemaria, Silvia C Formenti
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00325/full