Design Principles of Pancreatic Islets: Glucose-Dependent Coordination of Hormone Pulses.

Pancreatic islets are functional units involved in glucose homeostasis. The multicellular system comprises three main cell types; β and α cells reciprocally decrease and increase blood glucose by producing insulin and glucagon pulses, while the role of δ cells is less clear. Although their spatial o...

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Bibliographic Details
Main Authors: Danh-Tai Hoang, Manami Hara, Junghyo Jo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4818077?pdf=render