Comparative expression analysis of Shox2-deficient embryonic stem cell-derived sinoatrial node-like cells

Comparative expression analysis of Shox2-deficient embryonic stem cell-derived sinoatrial node-like cells

The homeodomain transcription factor Shox2 controls the development and function of the native cardiac pacemaker, the sinoatrial node (SAN). Moreover, SHOX2 mutations have been associated with cardiac arrhythmias in humans. For detailed examination of Shox2-dependent developmental mechanisms in SAN...

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Bibliographic Details
Main Authors: Sandra Hoffmann, Stefanie Schmitteckert, Anne Griesbeck, Hannes Preiss, Simon Sumer, Alexandra Rolletschek, Martin Granzow, Volker Eckstein, Beate Niesler, Gudrun A. Rappold
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Stem Cell Research
Subjects:
Shox2
Mouse embryonic stem cells
Transgenic cells
Differentiation model
Sinoatrial node-like cells
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117300624

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http://www.sciencedirect.com/science/article/pii/S1873506117300624

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