Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors

Long Non-coding RNA NEAT1: A Novel Target for Diagnosis and Therapy in Human Tumors

The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with worse survival in cancer patients. NEAT1 drives tumor initiation and progression by modulating the expression of genes involved in...

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Bibliographic Details
Main Authors: Peixin Dong, Ying Xiong, Junming Yue, Sharon J. B. Hanley, Noriko Kobayashi, Yukiharu Todo, Hidemichi Watari
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Genetics
Subjects:
NEAT1
nuclear paraspeckle assembly transcript 1
long non-coding RNA
cancer diagnosis
cancer treatment
EMT
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00471/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00471/full

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