Calreticulin Mutations in Myeloproliferative Neoplasms: Comparison of Three Diagnostic Methods.

Calreticulin (CALR) mutations have recently been reported in 70-84% of JAK2V617F-negative myeloproliferative neoplasms (MPN), and this detection has become necessary to improve the diagnosis of MPN. In a large single-centre cohort of 298 patients suffering from Essential Thrombocythemia (ET), the JA...

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Main Authors: Ji-Hye Park, Margaux Sevin, Selim Ramla, Aurélie Truffot, Tiffany Verrier, Dominique Bouchot, Martine Courtois, Mathilde Bas, Sonia Benali, François Bailly, Bernardine Favre, Julien Guy, Laurent Martin, Marc Maynadié, Serge Carillo, François Girodon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4621046?pdf=render