Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma

Whether the perivascular niche (PVN) and the integration into multicellular networks by tumor microtubes (TMs) have a different role in glioblastoma progression and resistance to therapies is currently unclear. Here, the authors, by long-term tracking of individual glioma, demonstrate that both nich...

Full description

Bibliographic Details
Main Authors: Erik Jung, Matthias Osswald, Miriam Ratliff, Helin Dogan, Ruifan Xie, Sophie Weil, Dirk C. Hoffmann, Felix T. Kurz, Tobias Kessler, Sabine Heiland, Andreas von Deimling, Felix Sahm, Wolfgang Wick, Frank Winkler
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-21117-3