Rapid direct action of estradiol in GnRH neurons: findings and implications
Estradiol plays a pivotal role in the control of GnRH neuronal function and female reproduction. While positive and negative feedback actions of estradiol that enhance and suppress release of GnRH and LH are primarily mediated through estrogen receptor alpha (ERα) located in interneurons, a series o...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-01-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00106/full |