Evolving Concepts of Reflux: The Ups and Downs of the LES

The common denominator for virtually all episodes of gastroesophageal reflux in health and disease is the loss of the barrier that confines the gastric environment to the stomach. Factors important in the function of the barrier are its pressure, length and position. In early reflux disease, overeat...

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Bibliographic Details
Main Author: Tom R DeMeester
Format: Article
Language:English
Published: Hindawi Limited 2002-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2002/652650