Acute neuropathological consequences of short-term mechanical ventilation in wild-type and Alzheimer’s disease mice

Abstract Background Mechanical ventilation is strongly associated with cognitive decline after critical illness. This finding is particularly evident among older individuals who have pre-existing cognitive impairment, most commonly characterized by varying degrees of cerebral amyloid-β accumulation,...

Full description

Bibliographic Details
Main Authors: Shouri Lahiri, Giovanna C. Regis, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Elizabeth H. Kim, Mitra Mastali, Jennifer E. Van Eyk, Padmesh S. Rajput, Patrick D. Lyden, Keith L. Black, E. Wesley Ely, Heather D. Jones, Maya Koronyo-Hamaoui
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-019-2356-2