Genetic Variants of C-5312T REN Increased Renin Levels and Diastolic Blood Pressure Response to Angiotensin Receptor Blockers

Renin catalyzes the cleavage of angiotensinogen into angiotensin I. Genetic variant C-5312T of renin enhancer has been reported to increase in vitro renin gene transcription. However, no obvious in vivo study was performed to see the renin level in C-5312T when treated with angiotensin receptor blo...

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Bibliographic Details
Main Authors: Mohammad Saifur Rohman, Ika Arum Dewi Satiti, Nashi Widodo, Mifetika Lukitasari, Hidayat Sujuti
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:International Journal of Hypertension
Online Access:http://dx.doi.org/10.1155/2015/930631