Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development.

Cholecystokinin (CCK), a peptide hormone and one of the most abundant neuropeptides in vertebrate brain, mediates its actions via two G-protein coupled receptors, CCKAR and CCKBR, respectively active in peripheral organs and the central nervous system. Here, we demonstrate that the CCK receptors hav...

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Bibliographic Details
Main Authors: Sayoko Nishimura, Kaya Bilgüvar, Keiko Ishigame, Nenad Sestan, Murat Günel, Angeliki Louvi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4398320?pdf=render