Characterization of the Primary Human Trophoblast Cell Secretome Using Stable Isotope Labeling With Amino Acids in Cell Culture

Characterization of the Primary Human Trophoblast Cell Secretome Using Stable Isotope Labeling With Amino Acids in Cell Culture

The placental villus syncytiotrophoblast, the nutrient-transporting and hormone-producing epithelium of the human placenta, is a critical regulator of fetal development and maternal physiology. However, the identities of the proteins synthesized and secreted by primary human trophoblast (PHT) cells...

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Bibliographic Details
Main Authors: Fredrick J. Rosario, Sammy Pardo, Trond M. Michelsen, Kathryn Erickson, Lorna Moore, Theresa L. Powell, Susan T. Weintraub, Thomas Jansson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
placenta
pregnancy
maternal-fetal exchange
mass spectrometry relative protein synthesis rates
proteomics
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.704781/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.704781/full

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