Engineered models of tumor metastasis with immune cell contributions

Summary: Most cancer deaths are due to tumor metastasis rather than the primary tumor. Metastasis is a highly complex and dynamic process that requires orchestration of signaling between the tumor, its local environment, distant tissue sites, and immune system. Animal models of cancer metastasis pro...

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Bibliographic Details
Main Authors: Pamela L. Graney, Daniel Naveed Tavakol, Alan Chramiec, Kacey Ronaldson-Bouchard, Gordana Vunjak-Novakovic
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001474