Type of culture medium determines properties of cultivated retinal endothelial cells: induction of substantial phenotypic conversion by standard DMEM

Contradictory behavior of microvascular retinal endothelial cells (REC) - a reliable in vitro model to study retinal diseases - have recently been reported which might result from cultivating the cells in standard DMEM not optimized for this cell type. Therefore, we studied DMEM's effects on ph...

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Bibliographic Details
Main Authors: Catharina Busch, Matus Rehak, Margrit Hollborn, Peter Wiedemann, Gerhard K. Lang, Gabriele E. Lang, Armin Wolf, Heidrun L. Deissler
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021001420