How Does Circadian Rhythm Impact Salt Sensitivity of Blood Pressure in Mice? A Study in Two Close C57Bl/6 Substrains.

BACKGROUND:Mouse transgenesis has provided the unique opportunity to investigate mechanisms underlying sodium kidney reabsorption as well as end organ damage. However, understanding mouse background and the experimental conditions effects on phenotypic readouts of engineered mouse lines such as bloo...

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Bibliographic Details
Main Authors: Roy Combe, John Mudgett, Lahcen El Fertak, Marie-France Champy, Estelle Ayme-Dietrich, Benoit Petit-Demoulière, Tania Sorg, Yann Herault, Jeffrey B Madwed, Laurent Monassier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4835052?pdf=render