Label-free, High-Resolution Optical Metabolic Imaging of Human Cervical Precancers Reveals Potential for Intraepithelial Neoplasia Diagnosis

Summary: While metabolic changes are considered a cancer hallmark, their assessment has not been incorporated in the detection of early or precancers, when treatment is most effective. Here, we demonstrate that metabolic changes are detected in freshly excised human cervical precancerous tissues usi...

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Bibliographic Details
Main Authors: Dimitra Pouli, Hong-Thao Thieu, Elizabeth M. Genega, Laura Baecher-Lind, Michael House, Brian Bond, Danielle M. Roncari, Megan L. Evans, Francisca Rius-Diaz, Karl Munger, Irene Georgakoudi
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Cell Reports Medicine
Subjects:
HPV
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379120300227