Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

Recent evidence suggests that Alzheimer's disease (AD) and depression share common mechanisms of pathogenesis. In particular, deregulation of glutamate-mediated excitatory signaling may play a role in brain dysfunction in both AD and depression. We have investigated levels of glutamate and its...

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Bibliographic Details
Main Authors: Caroline Madeira, Charles Vargas-Lopes, Carlos Otávio Brandão, Taylor Reis, Jerson Laks, Rogerio Panizzutti, Sergio T. Ferreira
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Psychiatry
Subjects:
Alzheimer's disease
depression
glutamate
glutamine
cerebrospinal fluid
innotest amyloid tau index
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2018.00561/full

Internet

https://www.frontiersin.org/article/10.3389/fpsyt.2018.00561/full

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